Drug combination: Omnic tocas 0,4 & Rytmonorm & Spiriva respimat & Atoris 20 & Agen 5 & Pradaxa & Betaloc zok

Compared drugs
Omnic tocas 0,4 (tamsulosin)
Rytmonorm (propafenone)
Spiriva respimat (tiotropium bromide)
Atoris 20 (atorvastatin)
Agen 5 (amlodipine)
Pradaxa (dabigatran etexilate)
Betaloc zok (metoprolol)

Drug Interaction

Omnic tocas 0,4 & Agen 5
Tamsulosin may increase the hypotensive activities of Amlodipine.

Omnic tocas 0,4 & Betaloc zok
Metoprolol may increase the orthostatic hypotensive activities of Tamsulosin.

Rytmonorm & Pradaxa
The serum concentration of the active metabolites of Dabigatran etexilate can be increased when Dabigatran etexilate is used in combination with Propafenone.

Rytmonorm & Betaloc zok
The serum concentration of Metoprolol can be increased when it is combined with Propafenone.

Spiriva respimat & Betaloc zok
The metabolism of Tiotropium can be decreased when combined with Metoprolol.

Atoris 20 & Agen 5
The risk or severity of adverse effects can be increased when Amlodipine is combined with Atorvastatin.

Atoris 20 & Pradaxa
The serum concentration of Dabigatran etexilate can be decreased when it is combined with Atorvastatin.

Atoris 20 & Betaloc zok
The serum concentration of Metoprolol can be increased when it is combined with Atorvastatin.

Agen 5 & Pradaxa
The serum concentration of the active metabolites of Dabigatran etexilate can be increased when Dabigatran etexilate is used in combination with Amlodipine.

Agen 5 & Betaloc zok
The serum concentration of Metoprolol can be increased when it is combined with Amlodipine.

Pradaxa & Betaloc zok
The serum concentration of the active metabolites of Dabigatran etexilate can be increased when Dabigatran etexilate is used in combination with Metoprolol.

Food interactions and other recommendations

Omnic tocas 0,4: Take 30 minutes after a meal (always after the same meal). Taking the drug with food minimizes plasma levels variations.
Rytmonorm: Always take at the same time in regard to meals. Grapefruit and grapefruit juice should be avoided throughout treatment. Grapefruit can increase serum levels of this product.
Atoris 20: Avoid alcohol. Avoid drastic changes in dietary habit. Avoid taking grapefruit or grapefruit juice throughout treatment. Grapefruit can significantly increase serum levels of this product. Food may decrease maximum plasma levels and area under the curve, but this is clinically inconsequential according to the manufacturer. Take with low fat meal.
Agen 5: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Pradaxa: St. John's Wort
Betaloc zok: Avoid alcohol. Avoid natural licorice. Take with food.

Combination of side effects

Combination of common side effects of all medicines

For some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
Můžete si také zkusit zobrazit jednotlivá porovnání vedlejších účinků

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