Drug combination: Omnic tocas 0,4 & Rytmonorm & Spiriva respimat & Atoris 20 & Agen 5 & Pradaxa
Drug InteractionOmnic tocas 0,4 & Agen 5
Tamsulosin may increase the hypotensive activities of Amlodipine.
Rytmonorm & Pradaxa
The serum concentration of the active metabolites of Dabigatran etexilate can be increased when Dabigatran etexilate is used in combination with Propafenone.
Atoris 20 & Agen 5
The risk or severity of adverse effects can be increased when Amlodipine is combined with Atorvastatin.
Atoris 20 & Pradaxa
The serum concentration of Dabigatran etexilate can be decreased when it is combined with Atorvastatin.
Agen 5 & Pradaxa
The serum concentration of the active metabolites of Dabigatran etexilate can be increased when Dabigatran etexilate is used in combination with Amlodipine.
Food interactions and other recommendationsOmnic tocas 0,4: Take 30 minutes after a meal (always after the same meal). Taking the drug with food minimizes plasma levels variations.
Rytmonorm: Always take at the same time in regard to meals. Grapefruit and grapefruit juice should be avoided throughout treatment. Grapefruit can increase serum levels of this product.
Atoris 20: Avoid alcohol. Avoid drastic changes in dietary habit. Avoid taking grapefruit or grapefruit juice throughout treatment. Grapefruit can significantly increase serum levels of this product. Food may decrease maximum plasma levels and area under the curve, but this is clinically inconsequential according to the manufacturer. Take with low fat meal.
Agen 5: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Pradaxa: St. John's Wort
Combination of side effects Combination of common side effects of all medicinesFor some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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