Drug combination: Orcal neo & Vizarsin & Medrol & Trexan & Nebivolol sandoz

Compared drugs
Orcal neo (amlodipine)
Vizarsin (sildenafil)
Medrol (methylprednisolone)
Trexan (methotrexate)
Nebivolol sandoz (nebivolol)

Drug Interaction

Orcal neo & Vizarsin
Sildenafil may increase the antihypertensive activities of Amlodipine.

Orcal neo & Nebivolol sandoz
The risk or severity of adverse effects can be increased when Amlodipine is combined with Nebivolol.

Vizarsin & Medrol
The metabolism of Methylprednisolone can be decreased when combined with Sildenafil.

Vizarsin & Nebivolol sandoz
Sildenafil may increase the antihypertensive activities of Nebivolol.

Food interactions and other recommendations

Orcal neo: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Trexan: Milk appears to reduce its absorption. Take without regard to meals. Limit caffeine intake.

Combination of side effects

Combination of common side effects of all medicines

For some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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