Drug combination: Trombex & Egilok & Tezefort & Sortis & Nolpaza & Indapamid stada
Drug InteractionTrombex & Tezefort
The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Amlodipine.
Trombex & Nolpaza
The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Pantoprazole resulting in a loss in efficacy.
Egilok & Tezefort
The serum concentration of Metoprolol can be increased when it is combined with Amlodipine.
Egilok & Sortis
The serum concentration of Metoprolol can be increased when it is combined with Atorvastatin.
Egilok & Nolpaza
The metabolism of Metoprolol can be decreased when combined with Pantoprazole.
Egilok & Indapamid stada
The risk or severity of adverse effects can be increased when Metoprolol is combined with Indapamide.
Tezefort & Sortis
The risk or severity of adverse effects can be increased when Amlodipine is combined with Atorvastatin.
Tezefort & Indapamid stada
The risk or severity of adverse effects can be increased when Amlodipine is combined with Indapamide.
Food interactions and other recommendationsEgilok: Avoid alcohol. Avoid natural licorice. Take with food.
Tezefort: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Sortis: Avoid alcohol. Avoid drastic changes in dietary habit. Avoid taking grapefruit or grapefruit juice throughout treatment. Grapefruit can significantly increase serum levels of this product. Food may decrease maximum plasma levels and area under the curve, but this is clinically inconsequential according to the manufacturer. Take with low fat meal.
Nolpaza: Take without regard to meals.
Indapamid stada: Take without regard to meals. Magnesium, potassium and zinc needs increased.
Combination of side effects Combination of common side effects of all medicinesFor some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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